Serum gamma-glutamyl transferase: A novel biomarker for coronary artery disease

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Serum gamma-glutamyl transferase: A novel biomarker for coronary artery disease

BACKGROUND Atherosclerosis is a chronic inflammatory process, in which oxidative stress is the key event. Gamma-glutamyl transferase (GGT) is a cellular production of oxidants. We aimed to elucidate the relationship of serum GGT levels and coronary artery disease (CAD) in a Chinese population. MATERIAL AND METHODS A total of 513 adult subjects who had undergone coronary angiography were enrol...

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Gamma-glutamyl transferase: a novel cardiovascular risk biomarker.

Gamma-glutamyl transferase (GGT) is a second-generation enzymatic liver function test available for several decades, initially used as a sensitive indicator of alcohol ingestion, hepatic inflammation, fatty liver disease, and hepatitis. Longitudinal and cross-sectional investigational studies since 1990 have associated GGT with an increase in all-cause mortality, as well as chronic heart diseas...

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Association of coronary artery calcification and serum gamma-glutamyl transferase in Korean.

BACKGROUND AND OBJECTIVE Elevated serum gamma-glutamyl transferase (GGT) has been known to be associated with the cardiovascular disease. However, there is a lack of researches on direct examination of relevance between serum GGT and coronary artery calcification (CAC). Accordingly, the aim of this study was to investigate the association between serum GGT levels and the prevalence of CAC in Ko...

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Association of γ-glutamyl transferase with premature coronary artery disease

Accumulating evidence from epidemiological studies suggests that higher γ-glutamyl transferase (GGT) levels in the blood are associated with the incident of cardiovascular disease (CVD), including atherosclerosis, and have prognostic importance. However, to the best of our knowledge, the association of the GGT level with premature coronary artery disease (CAD) in an Asian Indian population has ...

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Gamma glutamyl transferase.

Serum gamma-glutamyl transferase (GGT) has been widely used as an index of liver dysfunction and marker of alcohol intake. The last few years have seen improvements in these areas and advances in understanding of its physiological role in counteracting oxidative stress by breaking down extracellular glutathione and making its component amino acids available to the cells. Conditions that increas...

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ژورنال

عنوان ژورنال: Medical Science Monitor

سال: 2014

ISSN: 1643-3750

DOI: 10.12659/msm.890245